University of Washington-Seattle Campus · PharmacologyBreastfeeding Pharmacology Lab
Mary F Hebert · Seattle, Washington
Research Focus
Dr. Mary Hebert's lab at the University of Washington focuses on understanding how medications taken by breastfeeding mothers can affect drug levels in breast milk. They employ advanced modeling techniques to predict how drugs may be transferred into breast milk based on various biological parameters. This research is crucial for assessing the safety of drug exposure for infants during breastfeeding and aims to fill significant gaps in current pharmacological knowledge.
breastfeedingdrug transferpharmacokineticstransportersbreast milksystems pharmacologyclinical studies
Research Aims
5AIM 01Evaluate transporter-mediated drug secretion into breast milk
AIM 02Develop predictive models using in vitro data
AIM 03Assess infant exposure risks from maternal medications
AIM 04Quantify protein abundance of transporters in mammary glands
AIM 05Bridge knowledge gaps in drug safety for breastfeeding infants
Skills the Lab Values
PBPK modelingquantitative proteomicsin vitro experimentationcell culturedata analysispharmacokinetic modelingtransport clearance calculationsexperimental design
Output against the department
Publications148bottom 42% of dept.269th of 462
this lab
most publishedleast published
Citations8.4ktop 44% of dept.204th of 462
this lab
most citedleast cited
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