University of Iowa · NeuroscienceThe Pain Modulation Lab
Yuriy M Usachev · Iowa City, Iowa
Research Focus
Dr. Yuriy Usachev's lab at the University of Iowa focuses on understanding the neural circuits that regulate pain. They study a newly discovered group of neurons involved in descending pain modulation to uncover how these neurons can influence pain processing. Their work aims to find new ways to treat chronic pain, ultimately benefiting countless patients who suffer from ineffective pain management.
pain modulationchronic painneural circuitsdescending pathwaysneuropathic pain
Research Aims
3AIM 01Identify the role of LJA5 neurons in inflammatory and neuropathic pain models.
AIM 02Examine the functional significance of LJA5 neuron projections.
AIM 03Determine the synaptic mechanisms mediating the antinociceptive effects of LJA5 neurons.
Skills the Lab Values
chemogenetic manipulationbehavioral testingpatch-clamp recording2-photon microscopymouse models
Output against the department
Publications85bottom 26% of dept.498th of 671
this lab
most publishedleast published
Citations3.8kbottom 28% of dept.481st of 671
this lab
most citedleast cited
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