Rutgers University-New Brunswick · PharmacologyEnvironmental Chemicals and Reproductive Health Lab
Shuo Xiao · New Brunswick, New Jersey
Research Focus
Dr. Shuo Xiao's lab at Rutgers focuses on understanding how certain environmental chemicals and chemotherapy drugs affect female reproductive health. Their research investigates the harmful effects of per- and polyfluoroalkyl substances (PFAS), known for their persistence in the environment, on ovarian function. Additionally, they explore the mechanisms through which cancer treatments cause ovarian damage and potential strategies to protect women's fertility during cancer therapy.
PFASovarian functionchemotherapyfemale fertilityDNA damagepubertydrug development
Research Aims
3AIM 01Investigate the effects of PFAS on gonadotropin-dependent folliculogenesis and ovulation.
AIM 02Determine the mechanistic roles of PPAR in PFAS-induced ovarian toxicity.
AIM 03Elucidate how JNK regulates apoptotic signaling in oocytes after chemotherapy exposure.
Skills the Lab Values
mouse modelsin vitro culture techniquesmolecular biology techniquesWestern blotPCRflow cytometrycomputer modelingepidemiological analysisbiostatistics
Output against the department
Publications103bottom 27% of dept.337th of 462
this lab
most publishedleast published
Citations3.7kbottom 27% of dept.335th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.