University of Florida · GeneticsIntestinal Immunity and Viral Response Lab
Megan L Stanifer · Gainesville, Florida
Research Focus
Dr. Megan Stanifer's lab at the University of Florida focuses on understanding how human intestinal cells respond to rotavirus infections. The team studies different types of interferons, proteins that help the body fight viruses, and how these proteins can be activated by various cellular pathways. Their research aims to improve strategies for combating rotavirus infections, especially in areas where vaccines are less effective.
rotavirusinterferonintestinal epithelial cellsviral infectionimmune response
Research Aims
4AIM 01Investigate how rotavirus infection activates the STING pathway in intestinal cells.
AIM 02Determine the roles of different type III interferon subtypes in controlling rotavirus.
AIM 03Explore the mechanisms of interferon upregulation in response to viral infection.
AIM 04Evaluate potential therapeutic applications of type III interferons against rotavirus.
Skills the Lab Values
cell culturegenetic depletion techniquespharmacological inhibitionRNA analysislive cell imagingsignal transduction assaysviral infection models
Output against the department
Publications113bottom 36% of dept.165th of 259
this lab
most publishedleast published
Citations6.5kbottom 35% of dept.169th of 259
this lab
most citedleast cited
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