Ohio State University-Main Campus · NeuroscienceFilous Neuroprotection Lab
Angela R Filous · Columbus, Ohio
Research Focus
Dr. Angela Filous's lab at Ohio State University focuses on understanding how infections, particularly pneumonia, impact recovery after spinal cord injuries. They explore the mechanisms behind impaired recovery and aim to find ways to protect spinal cord function in patients. The lab uses various experimental models to investigate the cellular and molecular interactions involved in injury and repair processes following infection.
spinal cord injurypneumonianeuroprotectionimmune responsemyeloid cellscell signalingvascular integritytranscriptional changesbacterial infectionsinflammation
Research Aims
3AIM 01Investigate circulatory humoral factors contributing to pneumonia-induced spinal cord injury.
AIM 02Examine cell-specific transcriptional changes related to anti-microbial immunity.
AIM 03Analyze the relationship between pneumonia and vascular damage in spinal injury.
Skills the Lab Values
parabiosis models3D imagingmouse modelsimmunofluorescencecell culturebiological assaysgene expression analysisblood-brain barrier studiesfluorescent microscopyintravenous injections
Output against the department
Publications16bottom 2% of dept.655th of 671
this lab
most publishedleast published
Citations1.2kbottom 6% of dept.630th of 671
this lab
most citedleast cited
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