University of California-Riverside · ChemistryWang DNA Lab
Yinsheng Wang · Riverside, California
Research Focus
Dr. Yinsheng Wang's lab at the University of California Riverside focuses on studying how alkylating agents, which can be found in our environment, affect DNA and RNA. The research explores how these chemicals cause damage to our genetic material and the biological responses that occur to repair this damage. Ultimately, this work aims to better understand health risks from environmental toxins and find ways to prevent diseases caused by DNA and RNA alkylation.
alkylating agentsDNA damageRNA methylationmolecular pathologyDNA repairtranslesion synthesisepitranscriptomicsenvironmental toxicantshuman health effects
Research Aims
5AIM 01Examine the molecular mechanisms of DNA and RNA alkylation.
AIM 02Identify the proteins involved in recognizing DNA damage from alkylation.
AIM 03Investigate how translesion synthesis DNA polymerases function during DNA repair.
AIM 04Assess the role of RNA methylation in neurological diseases.
AIM 05Develop strategies for preventing health issues associated with environmental chemical exposure.
Skills the Lab Values
PCRcell cultureproteomicsRNA sequencingDNA damage assaymicroscopybioinformaticstranscriptional analysissignal transduction studies
Output against the department
Publications510top 17% of dept.36th of 216
this lab
most publishedleast published
Citations24ktop 19% of dept.42nd of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.