Johns Hopkins University · EngineeringHydrogel Innovations Lab
Honggang Cui · Baltimore, Maryland
Research Focus
Dr. Honggang Cui's lab at Johns Hopkins University focuses on developing innovative drug delivery systems, specifically using self-assembling nanofiber hydrogels to treat malignant brain tumors like glioblastoma. The research aims to enhance the local delivery of anticancer drugs while minimizing side effects, ultimately improving patient survival rates. They are particularly interested in how these hydrogels can effectively release drugs over time and diffuse throughout brain tissue after tumor removal.
nanofiber hydrogelsglioblastomadrug deliverycamptothecintumor resectionsustained releaseintraoperative therapycancer treatmentbiomedical engineeringlocal chemotherapy
Research Aims
3AIM 01Develop self-assembling nanofiber hydrogels utilizing camptothecin for tumor therapy.
AIM 02Optimize drug release rates to enhance treatment efficacy against glioblastoma.
AIM 03Evaluate hydrogel diffusion in tissue and its therapeutic effects in animal models.
Skills the Lab Values
hydrogel synthesisnanofiber technologydrug formulationanimal modelstissue engineeringin vivo experimentationpharmacokineticscell culture techniquesbiostatisticsmolecular characterization
Output against the department
Publications218top 43% of dept.120th of 278
this lab
most publishedleast published
Citations17ktop 24% of dept.68th of 278
this lab
most citedleast cited
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