University of Florida · NeuroscienceCognitive Aging and Brain Dynamics Lab
Sara N Burke · Gainesville, Florida
Research Focus
Dr. Sara N. Burke's lab focuses on understanding how aging affects brain function, particularly how changes in specific brain regions relate to cognitive decline in older adults. With an emphasis on the relationship between individual neurons and brain connectivity, the lab aims to develop interventions that could enhance cognitive abilities in aging populations. They use advanced imaging and neurophysiological techniques to explore these changes in rats, which can provide insights into human cognition as well.
cognitive agingAlzheimer's diseasefunctional connectivityneurophysiologybrain imagingneuronal activityprefrontal cortexmedial temporal lobeaging interventionsneural dynamics
Research Aims
3AIM 01Investigate how perirhinal cortex to prefrontal cortex neuron activity changes with aging.
AIM 02Explore if altering neuron activity can modify brain connectivity patterns.
AIM 03Identify the neural oscillation changes associated with aging-related connectivity disruptions.
Skills the Lab Values
functional magnetic resonance imaging (fMRI)neurophysiology techniquesanimal modelsbehavioral testingdata analysis in neurosciencemicroscopyelectrophysiologybiostatisticsneuroanatomyexperimental design
Output against the department
Publications131bottom 46% of dept.361st of 671
this lab
most publishedleast published
Citations4.7kbottom 34% of dept.441st of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.