UGUniversity of Georgia · Genetics
Fungal Disease Therapeutics Lab
Richard Brian Meagher · Athens, Georgia
Research Focus
Dr. Richard Brian Meagher's lab focuses on tackling invasive fungal diseases that pose serious health risks, particularly in immunocompromised patients. The lab has developed a novel drug delivery system using targeted liposomes that can improve the effectiveness of antifungal treatments, significantly enhancing their ability to combat infections caused by fungi such as Candida albicans and Aspergillus fumigatus. Their research aims to create substantial improvements in antifungal therapies, potentially saving many lives.
antifungal therapyliposomal drug deliveryCandida albicansAspergillus fumigatusimmunocompromised patientsfungal infectionstargeted therapeuticsDectin receptorsdrug resistance
Research Aims
5AIM 01Develop targeted liposomes for antifungal drug delivery.
AIM 02Improve efficacy of antifungal treatments in mouse models.
AIM 03Generalize technology for additional antifungal agents.
AIM 04Investigate the role of Dectin-3 in targeting capabilities.
AIM 05Assess therapeutic outcomes in vulnerable patient populations.
Skills the Lab Values
liposome preparationin vitro assaysanimal modelsmicroscopyflow cytometryWestern blotPCRdrug targeting techniquescell cultureantibody assays
Output against the department
Publications127bottom 40% of dept.154th of 259
this lab
most publishedleast published
Citations7.2kbottom 37% of dept.162nd of 259
this lab
most citedleast cited
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