University of Houston · EngineeringExosome Innovations Lab
Wei-Chuan Shih · Houston, Texas
Research Focus
Dr. Wei-Chuan Shih's lab at the University of Houston focuses on advancing cancer diagnostics by analyzing circulating tumor exosomes. These tiny vesicles contain important information from cancerous cells, and the lab is developing a novel microfluidic platform to streamline their profiling. This technology aims to improve the detection sensitivity and dynamic range of cancer biomarkers in patient samples without needing invasive blood withdrawal.
exosome profilingliquid biopsycancer diagnosticsmicrofluidicsnanoplasmonic sensorsmolecular imagingbiomarker detection
Research Aims
5AIM 01Develop microfluidic platforms for exosome separation and analysis.
AIM 02Enhance detection sensitivity for cancer biomarkers in blood samples.
AIM 03Create a comprehensive profiling system for surface proteins and internal RNA/DNA in individual exosomes.
AIM 04Eliminate the need for blood withdrawal in cancer diagnostics.
AIM 05Benchmark the technology against various biological samples for performance evaluation.
Skills the Lab Values
microfluidicsnanoplasmonic sensingoptical imagingsurface protein analysisRNA isolationexosome extractionspectroscopybiochip technologydata analysis using software
Output against the department
Publications210top 45% of dept.124th of 278
this lab
most publishedleast published
Citations4.3kbottom 32% of dept.188th of 278
this lab
most citedleast cited
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