University of Maryland, Baltimore · PharmacologyWilks Heme Lab
Angela Wilks · Baltimore, Maryland
Research Focus
Dr. Angela Wilks' lab at the University of Maryland Baltimore investigates how the bacterium Pseudomonas aeruginosa, a major cause of infections, acquires iron to survive in hostile environments. The lab focuses on two important heme uptake systems, exploring how these systems regulate bacterial behavior, such as movement and biofilm formation, in response to the availability of heme. The research aims to uncover potential new therapies to combat antibiotic resistance by disrupting these survival pathways.
heme uptake systemsPseudomonas aeruginosaantibiotic resistancebacterial signalingbiofilm formation
Research Aims
3AIM 01Characterize the heme sensing systems in Pseudomonas aeruginosa.
AIM 02Investigate the role of biliverdin in regulating bacterial behavior.
AIM 03Determine the transcriptional regulation of specific operons important for heme uptake.
Skills the Lab Values
bacterial geneticsWestern blottransmission electron microscopyproteomicsgene transcription analysis
Output against the department
Publications207top 43% of dept.195th of 462
this lab
most publishedleast published
Citations6.1kbottom 44% of dept.261st of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.