Indiana University-Purdue University-Indianapolis · Biomedical EngineeringWu Neuroimaging Lab
Yu-Chien Wu · Indianapolis, Indiana
Research Focus
Dr. Yu-Chien Wu's lab at Indiana University Indianapolis focuses on understanding neurodegenerative diseases like Alzheimer's by using advanced MRI techniques. The lab explores how these imaging methods can detect changes in brain synapses associated with memory decline. By studying animal models and applying findings to human health, they aim to improve early diagnosis and treatment options for Alzheimer's disease.
Alzheimer's DiseaseMRINeurodegenerationSynaptic DensityImaging Biomarkers
Research Aims
3AIM 01Characterize the ability of diffusion MRI to detect changes in synaptic density in Alzheimer's disease models.
AIM 02Assess the translational potential of diffusion MRI metrics for human brain studies.
AIM 03Investigate the relationship between synaptic structure and cognitive decline in neurodegenerative disorders.
Skills the Lab Values
Diffusion MRIAnimal ModelsData AnalysisImage ProcessingSynaptic Structure Assessment
Output against the department
Publications194bottom 45% of dept.325th of 595
this lab
most publishedleast published
Citations3.3kbottom 25% of dept.445th of 595
this lab
most citedleast cited
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