University of Iowa · PsychologyThe Stress Resilience Lab
Jason J Radley · Iowa City, Iowa
Research Focus
Dr. Jason J. Radley's lab studies how the brain's neural circuits help mammals, including humans, respond to stress. They focus on understanding the mechanisms behind active and passive coping strategies when facing stressful situations. By examining how different parts of the brain communicate during stress, the lab aims to uncover ways to improve mental health and resilience against stress-related diseases.
neural circuitsstress copingoptogeneticsbehavioral neuroscienceHPA axispsychiatric diseasesrodent modelspassive copingactive copingchronic stress
Research Aims
4AIM 01Investigate how neural activity in specific brain pathways correlates with coping behaviors after chronic stress exposure.
AIM 02Evaluate the effects of inactivating certain neural pathways on HPA and sympathetic response under stress.
AIM 03Test whether enhancing activity in these pathways can restore adaptive coping behaviors in chronically stressed animals.
AIM 04Examine the interactions between different brain circuits to understand their roles in stress coping.
Skills the Lab Values
optogeneticsbehavioral assayschronic stress modelingneuroanatomical mappingviral vector techniquesphysiological monitoringdata recording and analysisanimal handlingsurgical techniquesimmunohistochemistry
Output against the department
Publications66bottom 14% of dept.252nd of 296
this lab
most publishedleast published
Citations6.8ktop 45% of dept.134th of 296
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.