Upstate Medical University · BiologyKrendel Lab
Mira Krendel · Syracuse, New York
Research Focus
Dr. Mira Krendel's lab at Upstate Medical University focuses on understanding how the protein myosin 1e affects kidney health, particularly in a type of cell called podocytes. By studying how mutations in this protein lead to kidney disease, the lab aims to develop potential strategies for protecting kidney functions and treating chronic kidney conditions. Overall, the research contributes to our understanding of kidney filtration and health.
myosin 1epodocyteskidney diseaseglomerular filtrationrenal function
Research Aims
3AIM 01Analyze the effects of disease-associated mutations on myosin 1e functions
AIM 02Determine the mechanisms of autoinhibition of myosin 1e activity
AIM 03Test the protective effects of myosin 1e activation on kidney function.
Skills the Lab Values
cell culturebiochemical assaysanimal modelsmolecular cloningimmunofluorescenceWestern blotRNA isolationPCR
Output against the department
Publications70bottom 19% of dept.833rd of 1,033
this lab
most publishedleast published
Citations3.1kbottom 23% of dept.791st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.