University of California-Los Angeles · EngineeringFungal Natural Products Discovery Lab
Yi Tang · Los Angeles, California
Research Focus
Dr. Yi Tang's lab at UCLA focuses on discovering and understanding natural products from fungi, which are small molecules with significant effects on health. The research highlights the biosynthesis processes these compounds undergo, particularly exploring unique enzymes that produce these natural products. Through innovative techniques, the lab seeks to unravel the chemical logic behind complex natural structures and find new compounds that can be beneficial for various health applications.
natural productsmetalloenzymesbiosynthesisfungienzyme discovery
Research Aims
5AIM 01Investigate the biosynthetic pathways of copper-dependent enzymes in fungi.
AIM 02Explore new families of amino acid-derived natural products.
AIM 03Characterize the sequence-function relationships of newly identified enzymes.
AIM 04Determine the mechanism of novel bond-forming logic in natural product biosynthesis.
AIM 05Utilize genomic information to discover unexplored natural product pathways.
Skills the Lab Values
genome miningbiochemical characterizationenzyme kineticsmolecular cloningsmall molecule isolation
Output against the department
Publications393top 17% of dept.48th of 278
this lab
most publishedleast published
Citations20ktop 19% of dept.53rd of 278
this lab
most citedleast cited
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