Indiana University-Purdue University-Indianapolis · BiologyCardiac Resilience Lab
Il-Man Kim · Indianapolis, Indiana
Research Focus
Dr. Il-Man Kim's lab focuses on understanding how to protect heart cells after a heart attack, which is crucial since the heart doesn't heal itself well. By studying specific molecules called microRNAs and their targets in heart cells and blood vessel cells, the lab aims to develop new therapies to improve heart healing and function. Their work combines laboratory models and human studies to explore how these molecules can be used to enhance recovery after heart damage.
myocardial infarctionmicroRNAscardiomyocyte survivalneovascularizationendothelial cellscardiac functionheart diseasetherapeutic strategies
Research Aims
3AIM 01Elucidate the role of PRSS23 as a target of endothelial miR-532 in heart conditions.
AIM 02Determine how the miR-532/PRSS23 axis influences cardiac remodeling and damage.
AIM 03Investigate paracrine mechanisms through which miR-532 impacts cardiomyocyte survival after ischemia.
Skills the Lab Values
mouse modelscell culturegene editingmolecular biology techniquesWestern blottingRNA isolationqPCRflow cytometry
Output against the department
Publications123bottom 44% of dept.579th of 1,033
this lab
most publishedleast published
Citations4.4kbottom 34% of dept.678th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.