MUSMedical University of South Carolina · Pharmacology
The GlycoFocus Lab
Anand S. Mehta · Charleston, South Carolina
Research Focus
Dr. Anand S. Mehta's lab focuses on developing new biomarkers for cholangiocarcinoma, a lethal form of liver cancer. The lab investigates changes in glycosylation patterns of proteins associated with cancer in order to improve diagnosis and prognosis for patients. They have developed an innovative method for analyzing these glycan changes using a streamlined antibody capture technique, aiming to enhance early detection and treatment options for cholangiocarcinoma.
glycosylationcholangiocarcinomabiomarkersliquid biopsyN-glycanscancer diagnosismass spectrometrymulti-institutional collaborationglyco-technology
Research Aims
5AIM 01Identify glycan changes in cholangiocarcinoma tissue and serum.
AIM 02Develop novel biomarkers based on glycosylation patterns.
AIM 03Validate biomarkers with multi-institutional collaborations.
AIM 04Streamline glycan analysis techniques for clinical applications.
AIM 05Enhance early detection methods for cholangiocarcinoma.
Skills the Lab Values
antibody array technologymass spectrometryglycan analysisserum sample processingbiomarker validationmultidisciplinary team collaborationdata interpretationcell cultureprotein purification
Output against the department
Publications369top 18% of dept.83rd of 462
this lab
most publishedleast published
Citations9.9ktop 38% of dept.177th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.