University of California-San Francisco · Biomedical EngineeringCardiac Metabolism Imaging Lab
Peder Eric Zufall Larson · San Francisco, California
Research Focus
Dr. Peder Eric Zufall Larson’s lab focuses on using advanced magnetic resonance imaging (MRI) techniques to understand heart disease, particularly how changes in heart metabolism can influence various heart conditions. By developing a specialized method called hyperpolarized 13C MRI, the lab aims to investigate metabolic remodeling in patients with hypertrophic cardiomyopathy, a common inherited heart condition. Their work has implications for better diagnosis and management of heart diseases through improved imaging processes.
hyperpolarized MRIcardiac metabolismheart diseaseglucose metabolismhypertrophic cardiomyopathymetabolic flexibilityexercise challenges
Research Aims
4AIM 01Develop hyperpolarized [1-13C]pyruvate MRI to evaluate cardiac metabolic changes.
AIM 02Translate imaging techniques into studies of hypertrophic cardiomyopathy (HCM) patients.
AIM 03Investigate the impact of HCM treatments on cardiac metabolic flexibility using MRI.
AIM 04Advance hyperpolarized MRI methods for improved resolution and metabolic insights.
Skills the Lab Values
MRI techniquesmetabolic imagingdata analysissubstrate availability assessmentexercise testingclinical research methodspatient interactionbiomarker analysisglucose tolerance testing
Output against the department
Publications385top 23% of dept.136th of 595
this lab
most publishedleast published
Citations9.7ktop 35% of dept.211th of 595
this lab
most citedleast cited
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