Vanderbilt University · EngineeringLuo Valvular Lab
Haoxiang Luo · Nashville, Tennessee
Research Focus
Professor Haoxiang Luo's lab at Vanderbilt University focuses on developing innovative solutions for heart valve diseases, especially aortic stenosis. They are investigating a new bioprosthetic aortic valve made from pulmonary visceral pleura, a tissue that may be more durable and resistant to degeneration compared to traditional materials. By conducting a series of mechanical and biological experiments, the lab aims to enhance the longevity and performance of transcatheter aortic valves used in minimally invasive surgeries.
bioprosthetic valvesaortic stenosistranscatheter aortic valve replacementpulmonary visceral pleurastructural valve degeneration
Research Aims
5AIM 01Develop a new bioprosthetic aortic valve from pulmonary visceral pleura.
AIM 02Evaluate mechanical durability and calcification resistance of the new valve material.
AIM 03Conduct in vivo studies to test the performance of the PVP valve in animal models.
AIM 04Use computational models to analyze hemodynamic performance and stress distributions.
AIM 05Investigate the long-term outcomes of PVP valves compared to existing bioprosthetic materials.
Skills the Lab Values
in vitro experimentsanimal modelscomputational modelingmechanical testinghigh-speed imaging
Output against the department
Publications348top 23% of dept.63rd of 278
this lab
most publishedleast published
Citations5.5kbottom 42% of dept.160th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.