University of North Texas Health Science Center · NeuroscienceSeshadri Lab
Sudha Seshadri · Fort Worth, Texas
Research Focus
Dr. Sudha Seshadri's lab at the University of Texas Health Science Center focuses on understanding dementia, especially in individuals over 85 years old. The lab studies how various factors like health, lifestyle, and genetics can influence cognitive health and the risk of developing dementia. They combine data from multiple long-term studies to uncover insights into why some people stay cognitively healthy into their nineties while others don't.
DementiaAgingCognitive HealthLongitudinal StudiesAlzheimer's DiseaseArtificial IntelligencePlasma BiomarkersVascular HealthSystemic IllnessResilience Factors
Research Aims
4AIM 01Relate midlife risk factors and MRI markers to late-life dementia risk and the likelihood of remaining dementia-free until age 85.
AIM 02Assess how multimorbidity affects life expectancy and dementia risk and model these factors with machine learning techniques.
AIM 03Examine biological pathways linking identified risk factors with dementia using plasma protein analyses.
AIM 04Investigate how factors like sex, age, and ethnicity affect dementia outcomes.
Skills the Lab Values
Statistical AnalysisBiological AssaysMachine LearningMagnetic Resonance Imaging (MRI)Blood Sample ProcessingPathway AnalysisLongitudinal Study DesignCohort CollaborationData HarmonizationPython Programming
Output against the department
Publications1,320top 2% of dept.12th of 671
this lab
most publishedleast published
Citations101ktop 2% of dept.15th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.