AECAlbert Einstein College of Medicine · Biology
Stem Cell Aging Research Lab
Maria Marianovich · Bronx, New York
Research Focus
Dr. Maria Marianovich's lab studies how the sympathetic nervous system influences the aging of blood-forming stem cells within the bone marrow. They aim to uncover the mechanisms that govern stem cell function and their environment as we age, which is crucial for understanding blood disorders and potential therapeutic strategies. Her research involves cutting-edge techniques and aims to reveal how nerve signals affect stem cell health and longevity.
hematopoietic stem cellsagingsympathetic nervous systemredox signalingmesenchymal stem cellsconnexin gap junctionsreactive oxygen speciescellular metabolismbone marrow microenvironment
Research Aims
2AIM 01Define the mechanisms of neural signal transduction in the stem cell niche.
AIM 02Investigate how metabolic changes in stromal cells influence hematopoietic stem cell aging.
Skills the Lab Values
cell cultureNADPH oxidase assaysfluorescence microscopypharmacological manipulationgenetic engineeringco-culture techniquesWestern blotflow cytometryRNA isolation
Output against the department
Publications4bottom 1% of dept.1,025th of 1,033
this lab
most publishedleast published
Citations1bottom 1% of dept.1,026th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.