Johns Hopkins University · Biomedical EngineeringWang Neurobiology Lab
Xiaoqin Wang · Baltimore, Maryland
Research Focus
Dr. Xiaoqin Wang's lab at Johns Hopkins University focuses on developing tools for gene editing in marmosets, which are small primates that can serve as valuable models for studying human brain diseases. The lab works on refining genetic manipulation techniques to create genetically modified marmosets that can help us understand brain function and neurobiology. By establishing a colony of marmosets and employing advanced genetic technologies, the research aims to generate innovative models that could pave the way for new therapies for brain-related disorders.
gene editingmarmosetsneurobiologyCRISPRgenetic manipulationbrain diseasesassisted reproductionbehavioral testing
Research Aims
3AIM 01Improve technology for in vitro genetic manipulation of marmosets.
AIM 02Identify safe harbor loci for genetic modifications.
AIM 03Generate marmoset models relevant to human brain diseases.
Skills the Lab Values
CRISPRembryo culturein vitro fertilizationgenetic manipulationmarmoset careneurobehavioral testingelectroporationpreimplantation screeningCre-lox technology
Output against the department
Publications227top 46% of dept.270th of 595
this lab
most publishedleast published
Citations12ktop 29% of dept.174th of 595
this lab
most citedleast cited
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