UTHThe University of Texas Health Science Center at Houston · Microbiology & Immunology
Lee Lab
Jayhun Lee · Houston, Texas
Research Focus
Dr. Jayhun Lee's lab studies a human parasite called Schistosoma mansoni, which can evade the immune system and thrive in the human bloodstream. The lab is particularly interested in how the parasite's esophageal gland helps it survive by breaking down immune cells that are supposed to fight it. By identifying specific proteins in this gland, the research aims to find new ways to treat schistosomiasis, a disease that affects millions worldwide.
Schistosoma mansoniimmune evasionesophageal glandschistosomiasishost-parasite interaction
Research Aims
3AIM 01Define the esophageal gland cell types and genes.
AIM 02Determine the role of specific esophageal gland factors in immune cell lysis.
AIM 03Investigate the mechanisms of specific esophageal gland factors in host-parasite interactions.
Skills the Lab Values
RNA sequencingRNA interferencein vitro assaysmolecular biology techniquescell culture
Output against the department
Publications17bottom 3% of dept.470th of 486
this lab
most publishedleast published
Citations779bottom 4% of dept.466th of 486
this lab
most citedleast cited
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