EUEmory University · Pharmacology
Li Lab
Lian Li · Atlanta, Georgia
Research Focus
Dr. Lian Li's lab at Emory University focuses on understanding Alzheimer's disease (AD) through groundbreaking research aimed at identifying new biomarkers and therapeutic targets. The lab investigates the role of glycosylation, particularly sialylation, in AD pathology by analyzing human brain specimens to uncover critical molecular changes. Their work aims to improve diagnosis and develop potential new interventions for this complex disease.
Alzheimer's diseasebiomarkersglycosylationsialylationglycoproteomicsprotein modificationsdisease mechanismstarget discoveryneurodegeneration
Research Aims
4AIM 01Discover novel glycosylation-based biomarkers for Alzheimer's disease.
AIM 02Identify sialoglycoproteomic networks involved in AD pathogenesis.
AIM 03Investigate alterations in protein glycoforms linked to Alzheimer's disease.
AIM 04Analyze patient specimens to monitor disease progression through biomarkers.
Skills the Lab Values
protein glycosylation analysissialoglycoproteomicsquantitative glycoproteomicscerebrospinal fluid collection and analysisblood serum sample processingmass spectrometrycell culture techniquesmolecular biology techniquesdata analysis in systems biology
Output against the department
Publications317top 24% of dept.113th of 462
this lab
most publishedleast published
Citations30ktop 9% of dept.42nd of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.