University of Pennsylvania · Biomedical EngineeringHaris Lab
Mohammad Haris · Philadelphia, Pennsylvania
Research Focus
Dr. Mohammad Haris's lab focuses on understanding Alzheimer's disease by exploring the role of neuroinflammation and developing new imaging methods to monitor it. Their research aims to connect neuroinflammation to disease progression and metabolic changes in the brain through innovative techniques. By working with mouse models and advanced magnetic resonance spectroscopy methods, they hope to create new diagnostic tools that can improve how we detect and treat Alzheimer's disease.
Alzheimer's diseaseneuroinflammationimaging biomarkersastrocytesMRImetabolismanimal modelsketogenic dietbrain glucose
Research Aims
4AIM 01Develop noninvasive imaging biomarkers to track neuroinflammation in Alzheimer's disease.
AIM 02Investigate the relationship between acetate metabolism and astrocyte reactivity in a reactive astrogliosis model.
AIM 03Characterize spatiotemporal patterns of neuroinflammation and glucose metabolism in an Alzheimer's mouse model.
AIM 04Evaluate the effect of a ketogenic diet on neuroinflammation in Alzheimer's mice.
Skills the Lab Values
magnetic resonance spectroscopy (MRS)deuterium-magnetic-resonance-spectroscopy (DMRS)quantitative exchanged-label turnover MRS (qeltMRS)mouse modelscell cultureimmunohistochemistrydata analysisexperimental designlongitudinal studies
Output against the department
Publications155bottom 34% of dept.395th of 595
this lab
most publishedleast published
Citations10ktop 34% of dept.202nd of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.