University of California-Davis · PharmacologyYang Lab
Yang Kevin Xiang · Davis, California
Research Focus
Dr. Kevin Xiang Yang's lab at UC Davis focuses on understanding the molecular mechanisms behind heart failure and memory processes in the brain. The lab investigates how receptors and enzymes, such as adrenergic receptors and phosphodiesterases, influence cardiac function and the signaling pathways that regulate gene expression in neurons. The research aims to discover new therapeutic targets that could enhance heart function in heart failure and improve cognitive disorders.
cardiac signalingheart failureadrenergic receptorsphosphodiesterasesgene expressioncAMP signalingneurobiologylearning and memorycalcium signaling
Research Aims
3AIM 01Investigate the role of MAOA in regulating cardiac b1AR signaling in heart failure.
AIM 02Examine the internal signaling mechanisms of b1ARs within cardiac myocytes.
AIM 03Identify how phosphodiesterases modulate nuclear cAMP signaling during learning and memory.
Skills the Lab Values
cell culturemouse modelsWestern blotPCRfluorescence microscopypulldown assaysimmunoprecipitationbiochemical assaysexperimental designdata interpretation
Output against the department
Publications209top 42% of dept.193rd of 462
this lab
most publishedleast published
Citations7.7ktop 47% of dept.217th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.