University of Mississippi · PhysiologyKidney Vascular Response Lab
Heather A Drummond · University, Mississippi
Research Focus
Dr. Heather A. Drummond's lab focuses on understanding how kidney blood vessels respond to mechanical pressure changes. This research aims to uncover the roles of specific ion channels in helping these blood vessels constrict in response to pressure, which is crucial for protecting the kidneys from damage associated with hypertension. By identifying the mechanisms behind these responses, the lab hopes to advance knowledge that can improve treatment for kidney disease and associated health issues.
hypertensionmechanosensingion channelsrenal injuryvascular smooth musclepressure-induced constrictionchronic kidney diseaseelectrophysiologymechanotransduction
Research Aims
3AIM 01Investigate the functional characteristics of b/gENaC-ASIC2 channels in renal vascular smooth muscle cells.
AIM 02Determine the contributions of ENaC channels and TrpC6 to pressure-induced vascular constriction.
AIM 03Assess how loss of specific ion channel expressions affects kidney injury in hypertension.
Skills the Lab Values
Xenopus oocyte expression systemelectrophysiologycell cultureanimal modelscalcium imagingmolecular cloningprotein expressionimmunohistochemistryWestern blotting
Output against the department
Publications139bottom 45% of dept.156th of 286
this lab
most publishedleast published
Citations4.8kbottom 41% of dept.169th of 286
this lab
most citedleast cited
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