WFUWake Forest University · Biology
NanoTarget Lab
William H. Gmeiner · Winston-Salem, North Carolina
Research Focus
Dr. William H. Gmeiner's lab focuses on developing innovative nanotechnology solutions to enhance cancer treatment, specifically for metastatic colorectal cancer (mCRC). Their research is particularly centered on a specialized polymer designed to improve drug delivery and effectiveness while reducing toxicity. By utilizing advanced formulations, such as lipid nanoparticles, they aim to directly target tumors and improve the outcomes of chemotherapy.
nanotechnologymetastatic colorectal cancerdrug deliverylipid nanoparticlesfluoropyrimidine polymerschemotherapytumor targetingpreclinical modelspolyethylene glycol
Research Aims
3AIM 01Develop novel CF10 formulations to target metastatic colorectal cancer more effectively.
AIM 02Enhance the pharmacokinetic properties of CF10 using lipid nanoparticle technology.
AIM 03Investigate the use of polyethylene glycol for improved drug delivery systems.
Skills the Lab Values
nanodrug formulationanimal modelspharmacokineticsimmunohistochemistryLC-MS/MScell culture techniquesDNA polymer synthesisPEGylationin vitro assays
Output against the department
Publications186top 35% of dept.360th of 1,033
this lab
most publishedleast published
Citations3.3kbottom 25% of dept.775th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.