University of Chicago · BiochemistryFei Lab
Jingyi Fei · Chicago, Illinois
Research Focus
Dr. Jingyi Fei's lab at the University of Chicago focuses on understanding membraneless organelles (MLOs) in eukaryotic cells. These organelles, which consist of proteins and RNAs, play crucial roles in cellular processes and are linked to various diseases. The lab aims to develop new methods to study the organization and function of MLOs at high resolution, which could ultimately lead to better therapeutic strategies for related health conditions.
membraneless organellesphase separationtranscriptomic analysissuper-resolution imagingRNA-protein interactions
Research Aims
5AIM 01Develop methods for transcriptomic characterization of membraneless organelles
AIM 02Investigate spatial organization of transcripts within MLOs
AIM 03Analyze the impact of RNA localization on metabolism
AIM 04Create adaptable platforms for studying MLOs in various sample types
AIM 05Enhance understanding of MLO functions related to stress and disease
Skills the Lab Values
RNA sequencingsuper-resolution microscopyin situ reverse transcriptionprotein targetingcell culture
Output against the department
Publications107bottom 27% of dept.294th of 402
this lab
most publishedleast published
Citations4.1kbottom 22% of dept.314th of 402
this lab
most citedleast cited
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