North Carolina State University at Raleigh · BiologyWang Lab
Xiaoqiu Wang · Raleigh, North Carolina
Research Focus
Dr. Xiaoqiu Wang's lab studies how aging affects the uterus and its ability to support pregnancy. The team focuses on the molecular mechanisms that lead to reproductive challenges in women of advanced maternal age, particularly how certain proteins respond to hormones. By investigating these processes in mice and human cells, they aim to uncover ways to improve pregnancy outcomes for older women.
uterine agingprogesterone receptordecidualizationreproductive healthmolecular biology
Research Aims
5AIM 01Investigate the changes in uterine responsiveness to hormones with age.
AIM 02Identify the molecular mechanisms behind progesterone receptor function in the aging uterus.
AIM 03Characterize the role of SIRT1 in uterine decidualization.
AIM 04Translate findings from mouse models to human endometrial cells.
AIM 05Develop strategies to counteract reproductive aging effects on pregnancy outcomes.
Skills the Lab Values
CRISPRRNA sequencingsingle-cell ATAC-seqgenetic mouse modelscell culture
Output against the department
Publications192top 33% of dept.342nd of 1,033
this lab
most publishedleast published
Citations4.7kbottom 36% of dept.660th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.