University of California-Irvine · Mathematics & StatisticsZhang Genomics Lab
Jing Zhang · Irvine, California
Research Focus
The research lab led by Dr. Jing Zhang focuses on integrating advanced computational methods and genomic techniques to understand complex diseases like Alzheimer’s and the impacts of opioid use in people living with HIV. Their work involves studying molecular changes at the single-cell level, employing innovative artificial intelligence approaches, and validating findings through cutting-edge genomic technologies. This interdisciplinary lab aims to pioneer new insights into the interconnectedness of genetics, epigenetics, and disease mechanisms.
HIVOpioid Use DisorderAlzheimer's DiseaseSingle-Cell GenomicsDeep Learning
Research Aims
3AIM 01Develop AI methods to analyze single-nucleus sequencing data for understanding HIV and opioid use effects.
AIM 02Identify cell-type specific gene regulatory changes in response to opioid exposure.
AIM 03Construct personalized gene regulation models for Alzheimer's Disease using single-cell multiome data.
Skills the Lab Values
Single-Cell RNA SequencingCRISPR TechniquesGenomic Data AnalysisMachine LearningBioinformatics Software Development
Output against the department
Publications127bottom 22% of dept.102nd of 131
this lab
most publishedleast published
Citations48ktop 9% of dept.12th of 131
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.