University of California-San Diego · EngineeringChapelin Lab
Fanny Chapelin · La Jolla, California
Research Focus
Dr. Fanny Chapelin's lab focuses on advancing organ transplantation techniques through innovative imaging methods. They aim to improve immune tolerance in transplant patients by tracking regulatory T cells using MRI. The research seeks to develop safer and more effective therapies for minimizing organ rejection and enhancing graft survival, ultimately improving patient outcomes.
organ transplantationregulatory T cellsMRI imagingimmune tolerancegraft survivalcell therapyimmunomodulationex vivo modelshuman donor organscell tracking
Research Aims
5AIM 01Develop MRI techniques for real-time monitoring of Treg function in transplant models.
AIM 02Capture the behavior and distribution of infused regulatory T cells using advanced imaging.
AIM 03Utilize discarded human donor organs to study cell dynamics in a clinically relevant setting.
AIM 04Enhance therapeutic strategies for promoting graft tolerance after organ transplantation.
AIM 05Explore interactions between infused cells and the vascular and tissue compartments in organ models.
Skills the Lab Values
magnetic resonance imaging (MRI)cell isolation techniquesanimal modelshuman organ perfusionimmunofluorescencephenotype analysiscell labeling with microbeadslongitudinal tracking in vivodata analysis in preclinical modelshistopathology correlation
Output against the department
Publications36bottom 4% of dept.267th of 278
this lab
most publishedleast published
Citations692bottom 5% of dept.264th of 278
this lab
most citedleast cited
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