University of Michigan-Ann Arbor · Biomedical EngineeringGlioblastoma Metabolism Research Unit
Daniel R Wahl · Ann Arbor, Michigan
Research Focus
Dr. Daniel R Wahl's lab at the University of Michigan focuses on understanding and targeting the unique metabolism of glioblastoma, an aggressive form of brain cancer. The lab aims to develop innovative methods to measure metabolic activity in tumors, which can help doctors identify the best treatment strategies. By exploring how glioblastoma cells adapt their metabolism to resist treatments like radiation, the lab hopes to improve patient outcomes and discover new therapeutic approaches.
glioblastomametabolismradiation therapypurine synthesistherapeutic strategies
Research Aims
5AIM 01Develop new methods to measure metabolic pathway activity in glioblastoma tumors
AIM 02Investigate the role of purine metabolism in radiation resistance
AIM 03Evaluate the safety and efficacy of metabolic inhibitors combined with radiation
AIM 04Identify biomarkers to predict therapeutic response in glioblastoma patients
AIM 05Conduct clinical trials to assess new treatment strategies for glioblastoma
Skills the Lab Values
cell culturemouse modelsclinical trialsmass spectrometrymagnetic resonance imaging (MRI)
Output against the department
Publications385top 23% of dept.137th of 595
this lab
most publishedleast published
Citations6.4kbottom 48% of dept.307th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.