New York University · BiochemistryNeurotoxin Therapeutics Unit
Konstantin Ichtchenko · New York, New York
Research Focus
Dr. Konstantin Ichtchenko's lab focuses on developing new treatments for botulinum neurotoxin poisoning, a serious condition that can cause paralysis and respiratory failure. The team aims to create innovative therapeutics that can specifically target and neutralize the neurotoxin's harmful effects within nerve cells. Their work is not only relevant for addressing botulism but also has implications for treating other neurodegenerative diseases.
botulinum toxinneurotoxintherapeuticsnanobodiesneurodegenerative diseases
Research Aims
5AIM 01Develop novel therapeutics for botulinum neurotoxin poisoning.
AIM 02Utilize natural neuronal receptors to deliver treatments specifically to neurons.
AIM 03Create antidotes that can effectively neutralize the neurotoxin after exposure.
AIM 04Investigate methods to enhance intracellular delivery of therapeutic molecules.
AIM 05Explore applications of developed therapeutics for other neurodegenerative diseases.
Skills the Lab Values
cell cultureprotein expressionnanobody generationin vivo modelsin vitro assays
Output against the department
Publications33bottom 2% of dept.392nd of 402
this lab
most publishedleast published
Citations3.9kbottom 21% of dept.318th of 402
this lab
most citedleast cited
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