University of California-San Diego · BiologyCellular Aging and Longevity Lab
Nan Hao · La Jolla, California
Research Focus
Dr. Nan Hao's lab at UC San Diego focuses on understanding the biological processes of aging at the single-cell level. By integrating computational modeling and synthetic biology, the lab investigates how cellular aging impacts health and disease, with particular attention to diseases like cancer and neurodegenerative disorders. Through innovative experiments and predictive modeling, they aim to develop strategies for promoting longevity and mitigating age-related diseases.
agingsynthetic biologycomputational modelingcellular aginglongevitygene networkshealthspanmicrofluidicsproteostasiscell fate decisions
Research Aims
4AIM 01Understand the dynamics of single-cell aging using computational models.
AIM 02Engineer synthetic gene circuits to influence aging pathways.
AIM 03Investigate the interactions between aging and energy/protein homeostasis.
AIM 04Predict and simulate aging trajectories in single cells under various conditions.
Skills the Lab Values
computational modelingsynthetic biology techniquesmicrofluidicscell culturegenetic engineeringlive-cell imagingdata analysisgene expression profilingsystems biology
Output against the department
Publications272top 22% of dept.224th of 1,033
this lab
most publishedleast published
Citations7.8ktop 48% of dept.493rd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.