University of California-Irvine · PhysiologyWagar Lab
Lisa Wagar · Irvine, California
Research Focus
Professor Lisa Wagar's lab at UC Irvine focuses on understanding the immune responses to influenza viruses. Using a novel approach with human tonsil organoids, the lab investigates how different features of the host and the virus influence the effectiveness of immune responses. Their ultimate goal is to aid in the development of a universal influenza vaccine that could provide better protection against various influenza strains.
influenzaimmune responseuniversal vaccinetonsil organoidsadaptive immunity
Research Aims
4AIM 01Investigate the immune responses to influenza using tonsil organoids.
AIM 02Understand how host and antigen factors impact antibody responses.
AIM 03Define the cell-cell interactions in lymphoid tissues during infection.
AIM 04Identify predictors of effective immune responses to influenza antigens.
Skills the Lab Values
cell cultureflow cytometryimmune organoid developmentantibody array assaysmolecular imaging
Output against the department
Publications69bottom 14% of dept.247th of 286
this lab
most publishedleast published
Citations4.1kbottom 35% of dept.187th of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.