University of California-Los Angeles · BiologyReed Lab
Elaine F Reed · Los Angeles, California
Research Focus
Dr. Elaine F Reed's lab focuses on understanding the immune system's responses in organ transplant recipients, particularly how immunosuppressive therapies affect vaccine efficacy and transplant rejection. They are exploring the immune responses to SARS-CoV-2 vaccines in kidney transplant patients, investigating how specific treatment regimens influence immunity. Additionally, the lab examines the molecular mechanisms that lead to graft rejection and finds innovative ways to enhance transplant outcomes.
SARS-CoV-2immunosuppressionvaccine efficacytransplant rejectionHLA antibodieskidney transplantendothelial cellschronic allograft injuryimmune dysregulation
Research Aims
3AIM 01Investigate how mycophenolate mofetil affects immune responses to SARS-CoV-2 vaccination in kidney transplant recipients.
AIM 02Characterize the signaling pathways activated by HLA antibodies in endothelial cells during transplant rejection.
AIM 03Identify pre-vaccine immunological factors predicting protective responses to vaccination in immunocompromised patients.
Skills the Lab Values
cell cultureimmunohistochemistryflow cytometryELISARNA sequencingmouse modelsCRISPRWestern blotsingle-cell sequencing
Output against the department
Publications685top 4% of dept.37th of 1,033
this lab
most publishedleast published
Citations22ktop 17% of dept.180th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.