University of California-Davis · PhysiologyDixon Lab
Rose Ellen Dixon · Davis, California
Research Focus
Dr. Rose Ellen Dixon's lab focuses on understanding how aging affects heart function and the mechanisms behind cardiovascular diseases. The research investigates how cellular structures in heart cells malfunction as people age, leading to problems like diastolic dysfunction. By finding out how certain proteins and lipids behave in aging heart cells, the lab aims to uncover new ways to maintain heart health and improve the quality of life for older adults.
cardiac agingendosomal traffickingCaV1.2 channelsPIP2 metabolismdiastolic dysfunctioncardiomyocytelipid regulationcardiac functionAlzheimer's diseasecardiovascular health
Research Aims
3AIM 01Investigate age-associated changes in endosomal trafficking in cardiomyocytes.
AIM 02Analyze the effects of altered PIP2 metabolism on cardiac function in aging hearts.
AIM 03Develop strategies to restore normal endosomal function in aged heart cells.
Skills the Lab Values
cell culturelive-cell imaginglipid mass spectrometryWestern blotelectrophysiologyimmunofluorescenceproteomicsmolecular cloningendocytosis assaysanimal models
Output against the department
Publications88bottom 22% of dept.223rd of 286
this lab
most publishedleast published
Citations1.9kbottom 10% of dept.257th of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.