Washington State University · PharmacologyThe TAK1 Therapeutics Lab
Salah-Uddin Ahmed · Pullman, Washington
Research Focus
Dr. Salah-Uddin Ahmed's lab at Washington State University focuses on understanding the role of a protein called TAK1 in rheumatoid arthritis (RA). They study how TAK1 contributes to the inflammatory and invasive behaviors of synovial fibroblasts, which play a key role in RA pathology. The lab aims to develop targeted therapies using TAK1 inhibitors to improve treatment outcomes for patients suffering from this chronic disease.
rheumatoid arthritisTAK1synovial fibroblastsinflammationtherapeutic inhibitors
Research Aims
3AIM 01Investigate the role of TAK1 in the functions of rheumatoid arthritis synovial fibroblasts.
AIM 02Evaluate the impact of TAK1 inhibitors on inflammatory signaling pathways.
AIM 03Explore the therapeutic potential of TAK1 inhibition in preclinical models of rheumatoid arthritis.
Skills the Lab Values
Western blotRNA sequencingimmunoprecipitationcell cultureanimal modelschromatin assayspharmacological assessmentdata analysisdose-response testing
Output against the department
Publications182top 49% of dept.227th of 462
this lab
most publishedleast published
Citations4.1kbottom 31% of dept.318th of 462
this lab
most citedleast cited
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