University of Alabama at Birmingham · BiologyChen Lab
Shu G. Chen · Birmingham, Alabama
Research Focus
Dr. Shu G. Chen's lab at the University of Alabama at Birmingham is focused on finding accurate ways to diagnose neurodegenerative diseases like Alzheimer's disease and Lewy body dementia. They are developing innovative tests using skin samples to detect biomarkers associated with these conditions before symptoms become severe. The goal is to improve patient care through early diagnosis, which can lead to better treatment options.
Alzheimer's DiseaseLewy Body Dementiabiomarkersdiagnostic toolstauopathiesParkinson's Disease Dementiaskin samplesRT-QuIC assayneurodegenerative diseases
Research Aims
4AIM 01Develop premortem biomarkers for Alzheimer's disease and Lewy body dementia.
AIM 02Assess the effectiveness of skin tau and aSyn biomarkers for accurate diagnosis.
AIM 03Differentiate between Alzheimer's disease and Lewy body dementia using novel biomarkers.
AIM 04Utilize peripheral tissue sampling to enhance early detection of neurodegenerative diseases.
Skills the Lab Values
RT-QuIC assaybiopsy techniquesimmunoassaysclinical trial designepidemiological methodsdata analysispatient sample collectionbiomarker detectiontissue processing
Output against the department
Publications115bottom 41% of dept.614th of 1,033
this lab
most publishedleast published
Citations10ktop 36% of dept.377th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.