San Diego State University · ChemistryThe Chagas Care Lab
Laura-Isobel Mccall · San Diego, California
Research Focus
Dr. Laura-Isobel Mccall's lab at San Diego State University is researching ways to improve treatment for Chagas disease, a serious infection that can lead to heart failure. They are specifically studying L-carnitine, a substance that may help reduce cardiac damage caused by the infection without directly killing the parasite. Their goal is to better understand how L-carnitine works and to support its development as a new treatment option for patients suffering from this disease.
Chagas diseaseL-carnitinecardiac healthTrypanosoma cruzinovel treatment
Research Aims
3AIM 01Identify how L-carnitine affects cardiac fatty acid oxidation.
AIM 02Analyze the impact of L-carnitine on glucose oxidation.
AIM 03Evaluate L-carnitine's effects on cardiac contractility in experimental models.
Skills the Lab Values
metabolomic analysispharmacological analysisechocardiographycell cultureanimal models
Output against the department
Publications97bottom 21% of dept.171st of 216
this lab
most publishedleast published
Citations4.0kbottom 28% of dept.155th of 216
this lab
most citedleast cited
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