University of Connecticut · GeneticsLee Lab
Se-Jin Lee · Storrs, Connecticut
Research Focus
Dr. Se-Jin Lee's lab focuses on understanding how certain proteins regulate bone density and muscle growth. By using genetic and biochemical techniques, the team investigates complex signaling pathways, aiming to develop clinical strategies to treat conditions like bone loss and muscle wasting. The lab's work could lead to new therapies that enhance bone strength and improve muscle function.
transforming growth factor betamyostatinactivinbone densitymuscle growthextracellular signalingbinding proteinsgenetic models
Research Aims
4AIM 01Investigate the role of myostatin and related ligands in muscle growth regulation.
AIM 02Elucidate the extracellular components that regulate bone homeostasis.
AIM 03Examine the effects of specific binding proteins on bone structure.
AIM 04Study how signaling pathways interact to influence muscle and bone health.
Skills the Lab Values
genetic engineeringmouse modelsbiochemical assaysimmunohistochemistrycryosectioningcell culturePCRWestern blotRNA sequencing
Output against the department
Publications127bottom 40% of dept.155th of 259
this lab
most publishedleast published
Citations20ktop 29% of dept.74th of 259
this lab
most citedleast cited
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