Texas A&M University-College Station · BiologyPaternal Health and Development Lab
Michael C. Golding · College Station, Texas
Research Focus
Dr. Michael C. Golding's lab focuses on understanding how paternal alcohol use can influence the health and development of offspring. Specifically, they explore how alcohol consumption by fathers can lead to epigenetic changes that affect mitochondrial function and contribute to fetal alcohol spectrum disorders (FASDs). By studying these changes in transgenic mouse models, the lab aims to uncover the genetic and biological mechanisms behind these effects and how they can impact long-term health outcomes for children.
paternal alcohol useepigeneticsfetal alcohol spectrum disordersmitochondrial dysfunctionnoncoding RNAstransgenic mouse modelshealth outcomesoxidative stress
Research Aims
5AIM 01Investigate how paternal alcohol exposure affects offspring mitochondrial function.
AIM 02Determine the role of sperm-inherited noncoding RNAs in FASD outcomes.
AIM 03Examine the impact of paternal oxidative stress on fetal development.
AIM 04Identify the mechanisms through which paternal behavior influences child health.
AIM 05Explore the long-term health consequences of epigenetic inheritance related to alcohol exposure.
Skills the Lab Values
epigenetic analysistransgenic mouse modelingcell cultureRNA extractionPCRWestern blottingmicroscopybioinformaticsdata analysis
Output against the department
Publications133bottom 47% of dept.541st of 1,033
this lab
most publishedleast published
Citations3.0kbottom 22% of dept.801st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.