University of California-Los Angeles · GeneticsGoldberg Malaria Lab
Amy Goldberg · Los Angeles, California
Research Focus
Dr. Amy Goldberg's lab at UCLA focuses on understanding how malaria parasites, particularly those that come from primate populations, can infect humans and lead to outbreaks. By studying the genetics of these parasites, especially a type called P. simium from Brazil, the lab aims to uncover the changes that allow these parasites to jump from one species to another. This research is crucial for predicting and preventing new malaria cases and developing effective treatments.
malariazoonotic diseasesgenomicshost-parasite interactionsevolutionary biologytransgenic organismspopulation geneticsPlasmodium simiummalaria elimination
Research Aims
5AIM 01Characterize the genetic basis of host specificity in zoonotic malaria parasites.
AIM 02Investigate the evolutionary dynamics of malaria from primates to humans.
AIM 03Develop simulation models to understand malaria population histories.
AIM 04Identify genetic loci that are under selection across multiple hosts.
AIM 05Test the function of candidate loci using transgenic techniques.
Skills the Lab Values
whole-genome sequencingtransgenic organism developmentgenetic analysiscomputational modelingphylogenetic analysiscell cultureprotein structure modelingpopulation genetics techniquesdata simulation
Output against the department
Publications131bottom 42% of dept.151st of 259
this lab
most publishedleast published
Citations2.2kbottom 9% of dept.236th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.