University of North Carolina at Charlotte · BiologyAugusto Lab
Danillo G Augusto · Charlotte, North Carolina
Research Focus
Dr. Danillo Augusto's lab focuses on understanding pemphigus, an autoimmune disease that causes severe skin blistering. By using advanced genetic and immunological techniques, the lab aims to uncover the genetic factors that make certain individuals susceptible to this disease, especially in areas where environmental triggers are present. This research could lead to new insights into autoimmune diseases and potential treatments.
pemphigusautoimmunitygenetic susceptibilityMHCmulti-omics
Research Aims
5AIM 01Investigate genetic variants within the major histocompatibility complex (MHC) associated with pemphigus susceptibility.
AIM 02Analyze immune cell transcriptomes to identify potential disease mechanisms.
AIM 03Discover and validate novel autoantigens and their role in disease onset.
AIM 04Map the T-cell repertoires in pemphigus patients from endemic regions.
AIM 05Explore the relationship between environmental factors and genetic predisposition to pemphigus.
Skills the Lab Values
long-read sequencingsingle-cell RNA sequencing (scRNA-seq)massively parallel phage sequencinggene expression analysisimmune profiling
Output against the department
Publications89bottom 29% of dept.729th of 1,033
this lab
most publishedleast published
Citations1.6kbottom 10% of dept.932nd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.