University of Rochester · Microbiology & ImmunologyImmune Cell Dynamics Lab
Minsoo Kim · Rochester, New York
Research Focus
Dr. Minsoo Kim's lab explores how immune cells interact with other tissues in the body, particularly focusing on T cells, which are crucial for fighting infections and cancer. They study how these cells can be directed to target tissues without causing harmful side effects, especially in therapies like CAR-T cell treatment. Additionally, the lab investigates how certain immune cells promote the formation of long-lasting memory T cells that can quickly respond to infections, and how these processes are impacted during severe conditions like sepsis.
T cell therapymemory T cellssepsisimmune responsecardiovascular toxicityimmunotherapyGalectin-1CRISPRinfluenzamonocyte differentiation
Research Aims
5AIM 01Investigate how T cells respond to tissues post-infusion to minimize side effects.
AIM 02Study the role of Galectin-1 in enhancing T cell memory in the respiratory tract.
AIM 03Explore mechanisms controlling neutrophil accumulation in sepsis to reduce organ damage.
AIM 04Identify new strategies to improve T cell migration in cancer therapy.
AIM 05Determine how monocyte differentiation affects antiviral T cell responses.
Skills the Lab Values
intravital microscopyCRISPR/Cas9 gene editinghigh-throughput screeningmouse modelscell cultureflow cytometryWestern blot analysisvaccine designimmunological assaysdata analysis in immunology
Output against the department
Publications47bottom 10% of dept.439th of 486
this lab
most publishedleast published
Citations5.6kbottom 41% of dept.285th of 486
this lab
most citedleast cited
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