University of California-Berkeley · BiochemistryThe Epithelial Dynamics Lab
David Bilder · Berkeley, California
Research Focus
David Bilder's lab at UC Berkeley focuses on understanding the biology of epithelial tissues, which are essential for forming protective barriers in animals. The lab uses fruit flies, Drosophila, to study how these tissues develop their shapes and how they respond to injuries. This research aims to uncover important mechanisms that can help repair damaged organs and prevent congenital defects.
epithelial biologymorphogenesisDrosophilatissue repairextracellular matrixwound signalingTNF signalingsystemic responsedevelopmental biology
Research Aims
5AIM 01Investigate how developing epithelia respond to mechanical forces and extracellular matrix resistance.
AIM 02Determine the mechanisms behind the mechanical patterning of epithelial tissues.
AIM 03Explore systemic wound responses in distant organs following epithelial injury.
AIM 04Identify signaling pathways that communicate injury responses between tissues.
AIM 05Analyze the role of TNF signaling in tissue repair and inflammation.
Skills the Lab Values
Drosophila geneticsadvanced imaging techniquesbiochemical assayscell culturein vivo injury modelsdata analysismolecular biology techniquesCRISPRsignal transduction pathways
Output against the department
Publications114bottom 29% of dept.284th of 402
this lab
most publishedleast published
Citations9.5ktop 50% of dept.203rd of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.