Iowa State University · BiologyLi Vaccine Lab
Jianrong Li · Ames, Iowa
Research Focus
Dr. Jianrong Li's research lab focuses on developing innovative vaccines for gastrointestinal and respiratory viruses. One major project aims to create mucosal vaccines for norovirus, targeting a global health issue where no effective vaccines currently exist. Another project investigates RNA modifications in SARS-CoV-2, which could lead to improved treatments and vaccines against COVID-19. The lab combines advanced viral vector technology with cutting-edge genetic research to address critical public health challenges.
norovirusSARS-CoV-2mucosal vaccinesRNA modificationsvaccine developmentviral vectorimmunogenicitygastroenteritisCOVID-19public health
Research Aims
5AIM 01Develop multivalent mucosal vaccines for human noroviruses.
AIM 02Investigate RNA modifications in SARS-CoV-2.
AIM 03Screen immunogenicity of vaccine candidates in animal models.
AIM 04Evaluate the immune responses to norovirus vaccines in gnotobiotic piglets.
AIM 05Understand how RNA modifications influence virus replication and immune responses.
Skills the Lab Values
PCRcell cultureanimal modelsCRISPRRNA sequencingvaccine formulationimmunology techniquesvirus isolationhigh-throughput sequencingdata analysis
Output against the department
Publications626top 4% of dept.42nd of 1,033
this lab
most publishedleast published
Citations59ktop 3% of dept.36th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.