Augusta University · PhysiologyCardiac Metabolism Research Lab
Weiqin Chen · Augusta, Georgia
Research Focus
Dr. Weiqin Chen's lab focuses on understanding the role of a protein called BSCL2 in heart metabolism and function. They investigate how BSCL2 is involved in breaking down triglycerides, a type of fat, and how this process affects the health of heart cells. The ultimate goal is to uncover new insights that could lead to therapies for heart conditions caused by metabolic issues.
cardiomyopathyBSCL2lipid metabolismtriglyceride catabolismmitochondrial functionfatty acid oxidationmetabolic diseasescardiac functionlipotoxicity
Research Aims
5AIM 01Investigate BSCL2's role in cardiac lipid metabolism and its link to triglyceride breakdown.
AIM 02Identify specific mitochondrial proteins that interact with BSCL2 at the ER/mitochondria contact sites.
AIM 03Explore the implications of BSCL2-mediated pathways on cardiac health and disease.
AIM 04Assess the impact of BSCL2 deletion on cardiac function and metabolic balance.
AIM 05Develop potential therapeutic strategies based on findings related to BSCL2 and cardiac metabolism.
Skills the Lab Values
molecular biology techniquesmouse modelsproteomicsbiochemical assayscell culturelipid analysismetabolic measurementsWestern blottingimmunofluorescencegenetic engineering
Output against the department
Publications127bottom 40% of dept.172nd of 286
this lab
most publishedleast published
Citations2.9kbottom 23% of dept.221st of 286
this lab
most citedleast cited
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