Augusta University · PharmacologySu Lab
Huabo Su · Augusta, Georgia
Research Focus
Dr. Huabo Su's lab at Augusta University focuses on understanding the role of proteins involved in mitochondrial health and vascular smooth muscle function. The research aims to uncover how specific proteins, like Cullin 3, influence heart and blood vessel health, particularly under stress. By using advanced genetic models, the lab explores mechanisms that can help prevent or treat cardiovascular diseases.
mitochondrial healthvascular smooth muscle cellscardiomyocytesCullin 3neddylationheart failurevascular remodelingcardiovascular diseasesprotein degradationmitophagy
Research Aims
5AIM 01Investigate the role of Cullin 3 in maintaining mitochondrial homeostasis in cardiomyocytes.
AIM 02Assess the importance of neddylation in controlling the contractile phenotype of vascular smooth muscle cells.
AIM 03Examine how neddylation impacts VSMC metabolism and prevents lesion formation under hypercholesterolemic conditions.
AIM 04Explore the pathophysiological significance of Cullin 3 mutations on cardiac remodeling.
AIM 05Identify novel therapeutic targets to improve heart health by understanding mitochondrial dysfunction.
Skills the Lab Values
genetic engineeringmouse modelsimmunohistochemistryWestern blotcell culturePCRanimal surgeriespharmacological assaysmolecular cloningbiochemical assays
Output against the department
Publications273top 29% of dept.133rd of 462
this lab
most publishedleast published
Citations4.3kbottom 32% of dept.313th of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.